6-METHOXY-1,2,3,4-TETRAHYDRO-9 H-PYRIDO[3,4-B]INDOLE

6-METHOXY-1,2,3,4-TETRAHYDRO-9 H-PYRIDO[3,4-B]INDOLE - Names and Identifiers

Name	6-methoxy-1,2,3,4-tetrahydro-9H-pyrido(3,4-B)
Synonyms	6-meothbc 6-methoxytryptoline 6-methoxytetrahydro-beta-carboline 6-METHOXY-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE 6-methoxy-1,2,3,4-tetrahydro-9H-pyrido(3,4-B) 6-METHOXY-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE 6-methoxy-2,3,4,9-tetrahydro-1H-beta-carboline 4-b)indole,2,3,4,9-tetrahydro-6-methoxy-1h-pyrido( 6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole 2,3,4,9-tetrahydro-6-methoxy-1h-pyrido(3,4-b)indole 6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole 6-METHOXY-1,2,3,4-TETRAHYDRO-9 H-PYRIDO[3,4-B]INDOLE
CAS	20315-68-8
InChI	InChI=1/C12H14N2O/c1-15-8-2-3-11-10(6-8)9-4-5-13-7-12(9)14-11/h2-3,6,13-14H,4-5,7H2,1H3

6-METHOXY-1,2,3,4-TETRAHYDRO-9 H-PYRIDO[3,4-B]INDOLE - Physico-chemical Properties

Molecular Formula	C12H14N2O
Molar Mass	202.25
Density	1.198g/cm³
Melting Point	219-222°C(lit.)
Boling Point	388.6°C at 760 mmHg
Flash Point	188.8°C
Vapor Presure	3.03E-06mmHg at 25°C
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.639

6-METHOXY-1,2,3,4-TETRAHYDRO-9 H-PYRIDO[3,4-B]INDOLE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
RTECS	UV0725000
Hazard Class	IRRITANT

6-METHOXY-1,2,3,4-TETRAHYDRO-9 H-PYRIDO[3,4-B]INDOLE - Introduction

6-methoxy-1,2,3, 4-B, also known as TTIP, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
1. Appearance: Colorless to light yellow crystalline solid.
2. Melting Point: about 110-115 degrees Celsius.
3. Solubility: Soluble in organic solvents such as ether, chloroform and dimethylformamide, insoluble in water.

Use:
1. TTIP is often used as a catalyst in organic synthesis, especially for the synthesis of indole compounds.
2. It can also be used as a starting agent for polymer materials for the preparation of polymers and surface modifiers.
3. TTIP is also used in organic light-emitting diodes (OLED) and organic solar cells (OPV) and other fields.

Method:
TTIP can be obtained by the reaction of 4-oxopyrroloindole (1) with methyl iodide. The steps are as follows:
1. Add 1 and methyl iodide to dry chloroform to form a reaction mixture.
2. Stir the reaction mixture at room temperature for 2-4 hours.
3. Use ether to extract the resulting triiodomethyl indole material.
4. Transfer the ether solution to petroleum ether and stir for 10-20 minutes.
5. Filter the filtrate and wash the product with cold ether.
6. The solvent was concentrated by vacuum rotation to obtain the target compound TTIP.

Safety Information:
1. TTIP is irritating to the human body, and contact with skin and eyes may cause pain and redness. Direct contact should be avoided.
2. During use, you need to wear appropriate personal protective equipment, such as lab gloves and goggles.
3. TTIP should be stored in a dry, cool, ventilated place, away from heat and fire.
4. When manipulating and handling TTIP, follow the correct laboratory procedures and avoid inhaling gases and solutions.
5. In the event of accidental contact or accidental use of TTIP, consult a doctor immediately and inform the doctor of the chemicals used.

Last Update：2024-04-09 02:00:44